Research HighlightsOptimal drug delivery systems
A great challenge when dealing with severe diseases, such as cancer or diabetes, is the implementation of an appropriate treatment. Design of treatment protocols is not a trivial issue, especially since nowadays there is significant evidence that the type of treatment depends on specific characteristics of individual patients. Within this context, the aim of this project is to develop models and model based control and optimization methods and tools for biomedical drug delivery systems in the cases of diabetes, anaesthesia and blood cancer, i.e., leukaemia. This will ensure: (1) Reliable and fast calculation of the optimal drug dosage without the need for an on-line computer while taking into account the specifics and constraints of the patient model (personalised health care); (2) Flexibility to adapt to changing patient characteristics; Incorporation of the physician’s performance criteria; (3) Safety of the patients; as optimisation of drug infusion rates would reduce the side effects of treatment. |